Guillain-Barré Syndrome associated with Chikungunya virus infection:
a case report
DOI:
https://doi.org/10.34024/rnc.2018.v26.9863Palabras clave:
Guillain-Barré Syndrome, Chikungunya virus, infection, case reportResumen
Objective. The epidemic of infection by the Chikungunya virus currently represents one of the largest epidemiological occurrences in south and Central America, being considered a serious public health problem, since, in addition to the typical clinical symptomatology, there are reports of Associated neurological diseases, such as Guillain-Barré Syndrome. Guillain-Barré Syndrome is an acute inflammatory demyelinating polyneuropathy that leads to various functional impairments, such as flaccid paralysis, areflexia and muscular weakness. Method. A case of Guillain-Barré Syndrome was reported after infection by the chikungunya virus. Results. The case presented severe functional complications, with a picture of flaccid tetraparesis, with motor and sensory impairment, mainly in the left hemibody. Conclusion. From this perspective, from this report, and from reports of previous cases, it is considered that chikungunya virus infection may cause Guillain-Barré Syndrome, among other severe neurological complications, in an acute and progressive way, especially in areas considered endemic.
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15.Acevedo N, Waggoner J, Rodriguez M, Rivera L, Landivar J, Pinsky B, et al. Zika Virus, Chikungunya Virus, and Dengue Virus in Cerebrospinal Fluid from Adults with Neurological Manifestations, Guayaquil, Ecuador. Front Microbiol 2017;8:42. http://dx.doi.org/10.3389/fmicb.2017.00042
16.Dirlikov E, Major CG, Mayshack M, Medina N, Matos D, Ryff KR, et al. Guillain-Barré Syndrome During Ongoing Zika Virus Transmission - Puerto Rico, January 1–July 31, 2016. MMWR Morb Mortal Wkly Rep 2016;65:910-4. http://dx.doi.org/10.15585/mmwr.mm6534e1
17.Bonifay T, Prince C, Neyra C, Demar M, Rousset D, Kallel H, et al. Atypical and severe manifestations of chikungunya vírus infection in French Guiana: A hospital-based study. PLoS ONE 2018;13:e0207406. http://dx.doi.org/10.1371/journal.pone.0207406
18.Balavoine S, Pircher M, Hoen B, Herrmann-Storck C, Najioullah F, Madeux B, et al. Guillain-Barré Syndrome and Chikungunya: Description of All Cases Diagnosed during the 2014 Outbreak in the French West Indies. Am J Trop Med Hyg 2017;97:356-60. http://dx.doi.org/10.4269/ajtmh.15-0753
2.Puccioni-Sohler M, Roveroni N, Rosadas C, Ferry F, Peralta JM, Tanuri A. Dengue infection in the nervous system: lessons learned for Zika and Chikungunya. Arq Neuropsiquiatr 2017;75:123-6. https://doi.org/10.1590/0004-282X20160189
3.Agarwal A, Vibha D, Srivastava AK, Shukla G, Prasad K. Guillain-Barre syndrome complicating chikungunya virus infection. J Neurovirol 2017;23:504-7. https://doi.org/10.1007/s13365-017-0516-1
4.Anaya JM, Rodríguez Y, Monsalve DM, Vega D, Ojeda E, González-Bravo D, et al. A comprehensive analysis and immunobiology of autoimune neurological syndromes during the Zika virus outbreak in Cúcuta, Colombia. J Autoimmun 2017;77:123-38. https://doi.org/10.1016/j.jaut.2016.12.007
5.Mancera-Páez O, Román GC, Pardo-Turriago R, Rodríguez Y, Anaya JM. Concurrent Guillain-barré syndrome, transverse myelitis and encephalitis Post-zika: A case report and review of the pathogenic role of multiple arboviral immunity. J Neurol Sci 2018:395:207-9. https://doi.org/10.1016/j.jns.2018.09.028
6.Azevedo MB, Coutinho MSC, Silva MA, Arduini DB, Lima JDV, Monteiro R, et al. Neurologic manifestations in emerging arboviral diseases in Rio de Janeiro City, Brazil, 2015-2016. Rev Soc Bras Med Trop 2018;51:347-51. https://doi.org/10.1590/0037-8682-0327-2017
7.Malta JMAS, Vargas A, Leite PL, Percio J, Coelho GE, Ferraro AHA, et al. Síndrome de Guillain-Barré e outras manifestações neurológicas possivelmente relacionadas à infecção pelo vírus Zika em municípios da Bahia, 2015. Epidemiol Serv Saúde 2017;26:9-18. http://dx.doi.org/10.5123/s1679-49742017000100002
8.Nóbrega MEB, Araújo ELL, Wada MY, Leite PL, Dimech GS, Pércio J. Surto de síndrome de Guillain-Barré possivelmente relacionado à infecção prévia pelo vírus Zika, Região Metropolitana do Recife, Pernambuco, Brasil, 2015. Epidemiol Serv Saúde 2018;27:e2017039. http://dx.doi.org/10.5123/s1679-49742018000200016
9.Tang X, Zhao S, Chiu APY, Wang X, Yang L, He D. Analysing increasing trends of Guillain-Barré Syndrome (GBS) and dengue cases in Hong Kong using meteorological data. PLoS ONE 2017;12:e0187830. http://dx.doi.org/10.1371/journal.pone.0187830
10.Cerny T, Schwarz M, Schwarz U, Lemant J, Gérardin P, Keller E. The Range of Neurological Complications in Chikungunya Fever. Neurocrit Care 2017;27:447-57. http://dx.doi.org/10.1007/s12028-017-0413-8
11.Oehler E, Fournier E, Leparc-Goffart I, Larre P, Cubizolle S, Sookhareea C, et al. Increase in cases of Guillain-Barré syndrome during a Chikungunya outbreak, French Polynesia, 2014 to 2015. Euro Surveill 2015;20:30079. http://dx.doi.org/10.2807/1560-7917.ES.2015.20.48.30079
12.Vieira MACS, Costa CHN, Linhares AC, Borba AS, Henriques DF, Silva EVP, et al. Potential role of dengue virus, chikungunya virus and Zika virus in neurological diseases. Mem Inst Oswaldo Cruz 2018;113:e170538. http://dx.doi.org/10.1590/0074-02760170538
13.Mehta R, Soares CN, Medialdea-Carrera R, Ellul M, da Silva MTT, Rosala-Hallas A, et al. The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series. PLoS Negl Trop Dis 2018;12:e0006212. http://dx.doi.org/10.1371/journal.pntd.0006212
14.Cao-Lormeau VM, Blake A, Mons S, Lastère S, Roche C, Vanhomwegen J, et al. Guillain-Barré Syndrome outbreak caused by ZIKA vírus infection in French Polynesia. Lancet 2016;387:1531–9. http://dx.doi.org/10.1016/S0140-6736(16)00562-6
15.Acevedo N, Waggoner J, Rodriguez M, Rivera L, Landivar J, Pinsky B, et al. Zika Virus, Chikungunya Virus, and Dengue Virus in Cerebrospinal Fluid from Adults with Neurological Manifestations, Guayaquil, Ecuador. Front Microbiol 2017;8:42. http://dx.doi.org/10.3389/fmicb.2017.00042
16.Dirlikov E, Major CG, Mayshack M, Medina N, Matos D, Ryff KR, et al. Guillain-Barré Syndrome During Ongoing Zika Virus Transmission - Puerto Rico, January 1–July 31, 2016. MMWR Morb Mortal Wkly Rep 2016;65:910-4. http://dx.doi.org/10.15585/mmwr.mm6534e1
17.Bonifay T, Prince C, Neyra C, Demar M, Rousset D, Kallel H, et al. Atypical and severe manifestations of chikungunya vírus infection in French Guiana: A hospital-based study. PLoS ONE 2018;13:e0207406. http://dx.doi.org/10.1371/journal.pone.0207406
18.Balavoine S, Pircher M, Hoen B, Herrmann-Storck C, Najioullah F, Madeux B, et al. Guillain-Barré Syndrome and Chikungunya: Description of All Cases Diagnosed during the 2014 Outbreak in the French West Indies. Am J Trop Med Hyg 2017;97:356-60. http://dx.doi.org/10.4269/ajtmh.15-0753
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Publicado
2018-10-09
Cómo citar
Martins, D. C. ., Orsini, M. ., Mafra Moreno, A., Souza, N. ., Teixeira, S. ., Torres Rodrigues, M. ., … Roque de Souza, G. . (2018). Guillain-Barré Syndrome associated with Chikungunya virus infection: : a case report. Revista Neurociências, 26, 1–8. https://doi.org/10.34024/rnc.2018.v26.9863
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