Factors associated with dysphagia in stroke patients: a systematic review

Authors

DOI:

https://doi.org/10.34024/rnc.2021.v29.11940

Keywords:

Stroke, Deglutition Disorder, Speech therapy, Deglutition

Abstract

Introduction. Alteration in the swallowing process, called dysphagia, is related to the development of post-stroke complications, such as malnutrition, dehydration and pulmonary problems. Objective. To verify the factors associated with the severity of dysphagia in stroke patients. Method. The search for articles was conducted in the Scielo, Lilacs, Pubmed, Scopus, Bireme, and Web Of Science databases. There was no restriction on location and language, from 2015 to 2020. For the selection of studies, the combination based on Medical Subject Heading Terms (MeSH) was used. Three studies that scored ≥6 points according to the protocol for qualitative scoring were included in the search. Results. The included articles found a correlation between NIHSS score and the degree of dysphagia, with mild stroke being associated with normal swallowing and mild dysphagia; while severe stroke with severe dysphagia. All patients with NIHSS scores ≥16 had some degree of oropharyngeal dysphagia, and all patients at risk of aspiration had stroke in the middle cerebral artery territory. Combined lesions of the frontal operculum and insular cortex resulted in prolonged risk of aspiration. Dysphagia and aspiration in post-stroke patients was related to oral phase dysfunction. Conclusion. There is evidence that the functional integrity of the oral and cervical muscles represents an aggravating factor for dysphagia after stroke, aspiration is an aspect associated with dysphagia after stroke. However, there was no correlation between hemispheric location of the stroke lesion and dysphagia. 

Metrics

Metrics Loading ...

References

World Health Organization (WHO). The top 10 causes of death. (endereço na Internet) Geneva; 2020 (acessado em 25/01/2021). Disponível em: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death

Botelho TS, Neto CDM, Araújo FLC, Assis SC. Epidemiologia do acidente vascular cerebral no Brasil. Tema em Saúde 2016;16:361-77. http://temasemsaude.com/wp-content/uploads/2016/08/16221.pdf

Jacques A, Cardoso MCDAF. Acidente Vascular Cerebral e sequelas fonoaudiológicas: atuação em área hospitalar. Rev Neurocienc 2011;19:229-36. https://doi.org/10.34024/rnc.2011.v19.8371

Panara K, Ahangar ER, Padalia D. Physiology, swallowing. Treasure Island: StatPearls Publishing; 2021.

https://www.ncbi.nlm.nih.gov/books/NBK541071/

Silva LM. Disfagia orofaríngea pós-acidente vascular encefálico no idoso. Rev Bras Geriatr Gerontol 2006;9:93-106. https://doi.org/10.1590/1809-9823.2006.09028

Arnold M, Liesirova K, Broeg-Morvay A, Meisterernst J, Schlager M, Mono ML, et al. Dysphagia in acute stroke: incidence, burden and impact on clinical outcome. Plos One 2016;11:e0148424. https://doi.org/10.1371/journal.pone.0148424

Crary MA, Humphrey JL, Carnaby-Mann G, Sambandam R, Miller L, Silliman S. Dysphagia, nutrition, and hydration in ischemic stroke patients at admission and discharge from acute care. Dysphagia 2013;28:69-76. https://doi.org/10.1007/s00455-012-9414-0

Young EC, Durant-Jones L. Developing a dysphagia program in an acute care hospital: a needs assessment. Dysphagia 1990;5:159-65. https://doi.org/10.1007/s00455-012-9414-0

Teasell R, Foley N, Fisher J, Finestone H. The incidence, management, and complications of dysphagia in patients with medullary strokes admitted to a rehabilitation unit. Dysphagia 2002;17:115-20. https://doi.org/10.1007/s00455-001-0110-8

Takizawa C, Gemmell E, Kenworthy J, Speyer R. A systematic review of the prevalence of oropharyngeal dysphagia in stroke, Parkinson’s disease, Alzheimer’s disease, head injury, and pneumonia. Dysphagia 2016;31:434-41. https://doi.org/10.1007/s00455-016-9695-9

Bamford J, Sandercock P, Dennis M, Warlow C, Burn J. Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet 1991;337:1521-6. https://doi.org/10.1016/0140-6736(91)93206-o

Paciaroni M, Mazzotta G, Corea F, Caso V, Venti M, Milia P, et al. Dysphagia following stroke. Eur Neurol 2004;51:162-7. https://doi.org/10.1159/000077663

Hamidon BB, Nabil I, Raymond AA. Risk factors and outcome of dysphagia after an acute ischaemic stroke. Med J Malas 2006;61:553. https://pubmed.ncbi.nlm.nih.gov/17623955/

Doria S, Abreu MA, Buch R, Assumpção R, Nico MA, Ekcley CA, et al. Estudo comparativo da deglutição com nasofibrolaringoscopia e videodeglutograma em pacientes com acidente vascular cerebral. Rev Bras Otorrinolaringol 2003;69:636-42. https://doi.org/10.1590/S0034-72992003000500008

Gomes GF, Campos ACL, Pisani JC, Macedo Filho ED, Ribas Filho JM, Malafaia O, et al. Sonda nasoenteral, aspiração traqueal e pneumonia aspirativa em pacientes hospitalizados com doença cérebro-vascular complicada por disfagia orofaríngea. Arq Bras Cirurg Dig 2003;16:189-92. http://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&src=google&base=LILACS&lang=p&nextAction=lnk&exprSearch=355479&indexSearch=ID

Schelp AO, Cola PC, Gatto AR, Silva RGD, Carvalho LRD. Incidência de disfagia orofaríngea após acidente vascular encefálico em hospital público de referência. Arq Neuropsiquiatr 2004;62:503-6. https://doi.org/10.1590/S0004-282X2004000300023

Barros AFF, Fábio SRC, Furkim AM. Correlação entre os achados clínicos da deglutição e os achados da tomografia computadorizada de crânio em pacientes com acidente vascular cerebral isquêmico na fase aguda da doença. Arq Neuropsiquiatr 2004;64:1009-14. https://doi.org/10.1590/S0004-282X2006000600024

Gatto AR, Rehder MIBC. Comparação entre queixas de deglutição e achados videofluoroscópicos no paciente pós-acidente vascular encefálico. Rev CEFAC 2006;8:320-7. https://pesquisa.bvsalud.org/portal/resource/pt/lil-440053

Cuppari L. Nutrição Clínica no Adulto. 4.ed. São Paulo: Manole; 2019.

Moher D, Shamseer L, Clarke M. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev 2015;4:1. https://doi.org/10.1186/2046-4053-4-1

Pithon MM, Sant'anna LIDA, Baião FCS, Santos RL, Coqueiro RS, Maia LC. Assessment of the effectiveness of mouthwashes in reducing cariogenic biofilm in orthodontic patients: a systematic review. J Dentistr 2015;43:297-308. https://doi.org/10.1016/j.jdent.2014.12.010

Galovic M, Leisi N, Muller M, Weber J, Abela E, Kagi G, et al. Lesion Location Predicts Transient and Extended Risk of Aspiration After Supratentorial Ischemic Stroke. Stroke 2013;44:2760-7. https://doi.org/10.1161/strokeaha.113.001690

Otto DM, Ribeiro MC, Barea LM, Mancopes R, Almeida ST. Association between neurological injury and the severity of oropharyngeal dysphagia after stroke. CoDAS 2016;28:724-9. https://doi.org/10.1590/2317-1782/2016201513

Umay EK, Yilmaz V, Gundogdu I, Ozturk E, Gurcay E, Karaahmet O, et al. What Happens to Swallowing Muscles after Stroke? A Prospective Randomized Controlled Electrophysiological Study. Neurol India 2019;67:1459-66. https://doi.org/10.4103/0028-3886.273645

Daniels S, McAdam C, Brailey K, Foundas A. Clinical assessment of swallowing and prediction of dysphagia severity.Am J Speech Lang Pathol 1997;6:17-24. https://doi.org/10.1044/1058-0360.0604.17

De Angelis EC. Protocolo de avaliação clínica no leito. In: Jotz GP, De Angelis EC, Barros APB. Tratado da deglutição e disfagia: no adulto e na criança. Rio de Janeiro: Revinter; 2009; p.71-5.

Crary MA, Mann GD, Groher ME. Initial psychometric assessment of a functional oral intake scale for dysphagia in stroke patients. Arch Phys Med Rehabil 2005;86:1516-20. https://doi.org/10.1016/j.apmr.2004.11.049

Trapl M, Enderle P, Nowotny M, Teuschl Y, Matz K, Dachenhausen A, et al. Dysphagia bedside screening for acute-stroke patients: the gugging swallowing screen. Stroke 2007;38:2948-52. https://doi.org/10.1161/STROKEAHA.107.483933

Giannantoni NM, Minisci M, Brunetti V, Scarano E, Testani E, Vollono C, et al. Evaluation of pharyngeal muscle activity through nasopharyngeal surface electromyography in a cohort of dysphagic patients with acute ischaemic stroke. Acta Otorhinolaryngol Ital 2016;36:295-9. https://dx.doi.org/10.14639%2F0392-100X-1124

Wilmskoetter J, Bonilha L, Martin-Harris B, Elm JJ, Horn J, Bonilha HS. Mapping acute lesion locations to physiological swallow impairments after stroke. NeuroImage Clin 2019;22:101685. https://doi.org/10.1016/j.nicl.2019.101685

Martin RE, Goodyear BG, Gati JS, Menon RS. Cerebral cortical representation of automatic and volitional swallowing in humans. J Neurophysiol 2001;85:938-50. https://doi.org/10.1152/jn.2001.85.2.938

Lowell SY, Reynolds RC, Chen G, Horwitz B, Ludlow CL. Functional connectivity and laterality of the motor and sensory components in the volitional swallowing network. Exp Brain Res 2012;219:85-96. https://doi.org/10.1007/s00221-012-3069-9

Rolls ET. Functions of the anterior insula in taste, autonomic, and related functions. Brain Cogn 2015;110:4-19. https://doi.org/10.1016/j.bandc.2015.07.002

Barros AFF, Fábio SRC, Furkim AM. Correlação entre os achados clínicos da deglutição e os achados da tomografia computadorizada de crânio em pacientes com acidente vascular cerebral isquêmico na fase aguda da doença. Arq Neuropsiquiatr 2006;64:1009-14. https://doi.org/10.1590/S0004-282X2006000600024

Han DS, Chang YC, Lu C-H, Wang T-G. Comparison of disordered swallowing patterns in patients with recurrent cortical/subcortical stroke and first-time brainstem stroke. J Rehabil Med 2004;1:1. https://doi.org/10.1080/16501970410024163

Dziewas R, Teismann IK, Suntrup S, Schiffbauer H, Steinstraeter O, Warnecke T, et al. Cortical compensation associated with dysphagia caused by selective degeneration of bulbar motor neurons. Hum Brain Mapp 2009;30:1352-60. https://doi.org/10.1002/hbm.20603

Linden P, Siebens AA. Dysphagia: predicting laryngeal penetration. Arch Phys Med Rehabil 1983;64:281-4. https://pubmed.ncbi.nlm.nih.gov/6860100/

Kumar S, Doughty C, Doros G, Selim M, Lahoti S, Gokhale S, Schlaug G. Recovery of swallowing after dysphagic stroke: an analysis of prognostic factors. J Stroke Cerebrovasc Dis 2014;23:56-62. https://doi.org/10.1016/j.jstrokecerebrovasdis.2012.09.005

Martino R, Foley N, Bhogal S, Diamant N, Speechley M, Teasell R. Dysphagia after stroke: incidence, diagnosis, and pulmonary complications. Stroke 2005;36:2756-63. https://doi.org/10.1161/01.str.0000190056.76543.eb

Langdon PC, Lee AH, Binns CW. High incidence of respiratory infections in ‘nil by mouth’tube-fed acute ischemic stroke patients. Neuroepidemiol 2009;32:107-13. https://doi.org/10.1159/000177036

Lyons M, Smith C, Boaden E, Brady MC, Brocklehurst P, Dickinson H, et al. Oral care after stroke: where are we now? Eur Stroke J 2018;3:347-54. https://dx.doi.org/10.1177%2F2396987318775206

Schroeder MF, Daniels SK, McClain M, Corey DM, Foundas AL. Clinical and cognitive predictors of swallowing recovery in stroke. J Rehabil Res Develop 2006;43:301. https://doi.org/10.1682/jrrd.2004.12.0154

Terre R, Mearin F. Oropharyngeal dysphagia after the acute phase of stroke: predictors of aspiration. Neurogastroenterol Motil 2006;18:200-5. https://doi.org/10.1111/j.1365-2982.2005.00729.x

Rofes L, Muriana D, Palomeras E, Vilardell N, Palomera E, Alvarez‐Berdugo D, et al. Prevalence, risk factors and complications of oropharyngeal dysphagia in stroke patients: A cohort study. Neurogastroenterol Motil 2018;30:e13338. https://doi.org/10.1111/nmo.13338

Benfield J, Michou E. Dysphagia screening and assessment in the stroke unit. J Neurosci Nurs 2016;12(Sup2):S24-8. https://doi.org/10.12968/bjnn.2016.12.Sup2.S24

Costa MMB. Neural control of swallowing. Arq Gastroenterol 2018;55:61-75. https://doi.org/10.1590/S0004-2803.201800000-45

Kohyama K, Gao Z, Ishihara S, Funami T, Nishinari K. Electromyography analysis of natural mastication behaviour using varying mouthful quantities of two types of gels. Physiol Behav 2016;161:174-82. https://doi.org/10.1016/j.physbeh.2016.04.030

Swart BJ, Verheij JC, Beurskens CH. Problems with eating and drinking in patients with unilateral peripheral facial paralysis. Dysphagia 2003;18:267-73. https://doi.org/10.1007/s00455-003-0011-0

Krewski D, Barakat-Haddad C, Donnan J, Martino R, Pringsheim T, Tremlett H, et al. Determinants of neurological disease: synthesis of systematic reviews. Neurotoxicol 2017;61:266-89. https://doi.org/10.1016/j.neuro.2017.04.002

Morris H. Dysphagia in the elderly-a management challenge for nurses. J Nurs 2006;15:558-62. https://doi.org/10.12968/bjon.2006.15.10.21132

Sellars C, Bowie L, Bagg J, Sweeney MP, Miller H, Tilston J, et al. Risk factors for chest infection in acute stroke: a prospective cohort study. Stroke 2007;38:2284-91. https://doi.org/10.1161/strokeaha.106.478156

Marik PE, Kaplan D. Aspiration Pneumonia and Dysphagia in the Elderly. Chest 2003;124:328-36. https://doi.org/10.1378/chest.124.1.328

Baroni AFFB, Fábio SRC, Dantas RO. Risk factors for swallowing dysfunction in stroke patients. Arq Gastroenterol 2012;49:118-24. https://doi.org/10.1590/s0004-28032012000200005

Xerez DR, Carvalho YSV, Costa MMB. Estudo clínico e videofluoroscópico da disfagia na fase subaguda do acidente vascular encefálico. Radiol Bras 2004;37:9-14. https://doi.org/10.1590/S0100-39842004000100004

Published

2021-12-14

How to Cite

Vitorio Ymai Rosendo, B., Faustino Gonçalves, L. ., Mituuti, C. T., & Haas, P. (2021). Factors associated with dysphagia in stroke patients: a systematic review. Revista Neurociências, 29, 1–24. https://doi.org/10.34024/rnc.2021.v29.11940

Issue

Section

Revisão Sistemática
##plugins.generic.dates.received## 2021-03-30
##plugins.generic.dates.accepted## 2021-11-12
##plugins.generic.dates.published## 2021-12-14

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.