Low intensity laser therapy on regeneration of nervous tissue after spinal cord injury
DOI:
https://doi.org/10.34024/rnc.2015.v23.8033Keywords:
Low Intensity Laser Therapy, Spinal Cord, Wounds and InjuriesAbstract
Objective. Conduct a literature review about the low intensity laser therapy (LILT) action on regeneration of central nervous tissue after spinal cord injury (SCI). Method. We searched for articles on Medline, Scielo, and Lilacs, from 2002 to 2014, with the descriptors: low intensity laser therapy, spinal cord, wounds and injuries. Results. Seven studies related to the theme were identified. The animal model was used in most of them (86%), and one (14%) used human. The wavelength varied from 780-904 nm, dose of 1.59-20 J/cm, exposure time of 2-30 minutes, irradiation period of 5-21 consecutive days, and the study with humans conducted 40-57 sessions (not consecutive). The cited forms of irradiation were transcutaneous and punctual. Two studies used cell transplantation associated with LILT. The cause of SCI ranged from complete section, hemisection, and contusion. All studies showed positive results of LILT. Conclusion. LILT exerts effects on SCI, decreasing the inflammatory process, decreasing cytokines and chemokines, improving the distribution of fibrocartilage/elastin, increasing axonal budding, which consequently lessened cavitation at the lesion site, improved evoked somatosensory potential, and improved functional recovery.
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References
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