Vagal and deep neurostimulation in refractory epilepsy: a scoping review
DOI:
https://doi.org/10.34024/rnc.2024.v32.15666Keywords:
Deep brain stimulation, Vagus nerve stimulation, Refractory epilepsyAbstract
Objective. This scoping review aims to compare the effectiveness and collateral and adverse effects of Vagus Nerve Stimulation (VNS) and Deep Brain Stimulation (DBS) techniques in the treatment of refractory epilepsy. Method. The research question drawn from the Population/Patient/Problem, Intervention, Control/Comparison, Outcome (PICO) methodology guided the search in the BVS, SciELO and MEDLINE/PubMed databases. Results. 164 articles were identified, but only 7 of them were included. Neurostimulation techniques were analyzed for their effectiveness based on the percentage of reduction in convulsive crisis over a period of time, being analyzed in isolation, combined, or comparing them with each other. In both techniques, the percentage of effectiveness increases over time. Furthermore, although their combined use is apparently not harmful, there is not enough evidence to support that such application provides better results. Finally, it was noted that, although the effectiveness appears to be greater in DBS, more studies are still needed to confirm this statement. Conclusions. Although VNS is associated with fewer side effects, ECP tends to be more effective in reducing epileptic seizures in cases of refractory epilepsy. The choice between these approaches must be personalized, considering the individual needs of patients and the risks associated with each technique.
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References
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Copyright (c) 2024 Lívia Barbosa Cavalcanti, Caio César Leite Martins, Giovanna Rodrigues Lira, Helena Alessandrine Santiago Quintino, João Pedro de Almeida Roque Lisboa, Lays Sthefany Siqueira da Costa, Brícia Maia Leite Dantas, Ludmila Belo Ramos da Silva, Hugo Rafael de Souza e Silva
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Accepted 2024-01-12
Published 2024-01-18
