Neurosífilis e Variantes Clínicas
DOI:
https://doi.org/10.4181/RNC.2012.20.617.6pPalavras-chave:
ífilis, Sistema Nervoso Central, NeurossífilisResumo
Introdução. A neurossífilis é uma manifestação pouco frequente da infecção do sistema nervoso central (SNC) pelo Treponema pallidum. Casos. Nós relatamos três casos de neurossífilis. O caso 1 apresentava-se com envolvimento ocular: atrofia ótica à direita e neurite ótica à esquerda; o caso 2 uma forma meningovascular com Acidente Vascular Cerebral isquêmico; e o caso 3, uma forma meníngea, tinha como queixa principal cefaléias. Discussão. Os casos relatados apresentavam distintas formas de neurossífilis. O diagnóstico sorológico depende da presença de anticorpos: Veneral Disease Research Laboratory (VDRL) – não específico – e/ou Fluorescent Treponemal Antibody Absorption (FTA-ABS) – específico. Conclusão. Nos casos acima o FTA-ABS no líquor foi uma ferramenta importante para o diagnóstico de neurossífilis, mesmo nos pacientes que apresentam VDRL sérico negativo.
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Publicado: 2012-12-31