Neurosífilis e Variantes Clínicas

  • Adriana Moro Resident of Neurology, Florianópolis-SC, Brazil.
  • Alisson Pittol Bresciani Resident of Neurology, Florianópolis-SC, Brazil.
  • Marcus Victor de Oliveira Resident of Neurology, Florianópolis-SC, Brazil.
  • Pedro Henrique de Campos Albino Resident of Neurology, Florianópolis-SC, Brazil
  • Melina Moré Bertotti Resident of Neurosurgery, Florianópolis-SC, Brazil.
  • Ana Magda Bruscato MD, Neurologist, Neurology Residency Program Preceptor, Florianópolis- SC, Brazil.
  • Luiz Paulo Queiroz MD, PhD, Neurologist, Neurology Residency Program Preceptor, Head of the Neurology Residency, Florianópolis-SC, Brazil.
  • Paulo Mattosinho Filho MD, Neurologist, Neurology Residency Program Preceptor, Head of the Neurology Department, Florianópolis-SC, Brazil.
Palavras-chave: ífilis, Sistema Nervoso Central, Neurossífilis

Resumo

Introdução. A neurossífilis é uma manifestação pouco frequente da infecção do sistema nervoso central (SNC) pelo Treponema pallidum. Casos. Nós relatamos três casos de neurossífilis. O caso 1 apresentava-se com envolvimento ocular: atrofia ótica à direita e neurite ótica à esquerda; o caso 2 uma forma meningovascular com Acidente Vascu­lar Cerebral isquêmico; e o caso 3, uma forma meníngea, tinha como queixa principal cefaléias. Discussão. Os casos relatados apresentavam distintas formas de neurossífilis. O diagnóstico sorológico depende da presença de anticorpos: Veneral Disease Research Laboratory (VDRL) – não específico – e/ou Fluorescent Treponemal Antibody Absorption (FTA-ABS) – específico. Conclusão. Nos casos acima o FTA-ABS no líquor foi uma ferramenta importante para o diagnóstico de neuros­sífilis, mesmo nos pacientes que apresentam VDRL sérico negativo.

Métricas

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Publicado
2012-12-31
Como Citar
Moro, A., Bresciani, A. P., Oliveira, M. V. de, Albino, P. H. de C., Bertotti, M. M., Bruscato, A. M., Queiroz, L. P., & Filho, P. M. (2012). Neurosífilis e Variantes Clínicas. Revista Neurociências, 20(4), 546-551. https://doi.org/10.4181/RNC.2012.20.617.6p
Seção
Relato de Caso