Cohort study of vocal evaluation in subjects with Multiple Sclerosis

Authors

  • Raí dos Santos Santiago Universidade Federal do Espírito Santo - UFES
  • Carolina Fiorin Anhoque Universidade Federal do Espírito Santo - UFES

DOI:

https://doi.org/10.34024/rnc.2019.v27.9707

Keywords:

Multiple Sclerosis, Dysphonia, Quality of life, Fatigue, Mood disorders

Abstract

Aim: to characterize the vocal impact of subjects with multiples clerosis in their voice-related quality of life, identifying vocal symptoms, as well as symptoms of anxiety, depression and vocal fatigue. Methods: Were recruited Fifteen subjects from both genders whoattended the HUCAM neurology outpatient clinic. The subjects were evaluated independent of the presence of a demyelinating outbreak to perform perceptual-auditory assessment of voice, Quality of Life in Voice, Vocal Disadvantage Index, Vocal Fatigue Index, Beck Anxiety Inventory and Beck Depression Inventory at different times, repeating the proposed protocol. Results: The comparison of the self-assessment data after Five months showed statistically significant changes in the IDV, QVV, IFV and perceptual-auditory evaluation protocols in the Asthenia, Strain and Instability domains. There was continuation of the limitation and slow talk in theree valuation, and the subjects began to present sensory symptoms, which was not observed  in the first contact. Conclusion: it was detected that there is vocal alteration mainly manifested by asthenia, strain and instability. The subjects present an impact on voice quality of life, vocal fatigue in the domains of fatigue and vocal restriction and physical discomfort associated with voice, and worsening of vocal disadvantage throughout the course of the disease.

Metrics

Metrics Loading ...

References

O'Connor P, Canadian Multiple Sclerosis Working Group. Key issues in the diagnosis and treatment of multiple sclerosis. An overview. Neurology 2002;59(6 Supl 3):1-33.

http://dx.doi.org/10.1212/wnl.59.6_suppl_3.s1

Moreira MA, Tilbery CP, Lana-Peixoto MA, Mendes MF, Kaimen Maciel DR, Callegaro D. Aspectos históricos de La esclerosis múltiple. Rev Neurol 2002;34:378-83.

https://doi.org/10.33588/rn.3404.2001313

Kurtzke JF. A reassessment of the distribution of multiple sclerosis. Acta Neurol Scan 1975;51:110-57.

Callegaro D, Goldbaum M, Morais L. The prevalence of multiple sclerosis in the city of São Paulo, Brazil. Acta Neurol Scand 2001;104:208-13.

https://doi.org/10.1111/j.1600-0404.1975.tb01365.x

Lana-Peixoto MA, Frota E, Campos GB, Monteiro LP on behalf of the Brazilian Committee for Treatment and Research in Multiple Sclerosis. The prevalence of multiple sclerosis in Belo Horizonte, Brazil. Arq Neuropsiquiatr 2012;70:102-7.

http://dx.doi.org/10.1590/S0004-282X2012000200006

Rocha F, Herreira L, Morales RR. Multiple Sclerosis in Botucatu, Brazil - a population study. Mult Scler 2002;8(supl1):41.

Miller JR. Esclerose Múltipla. In: Rowland LP. Merritt Tratado de Neurologia. 10 ed. Rio de Janeiro: Guanabara Koogan; 2002, 887p.

Behlau M. Voz - O Livro do Especialista. vol 1. Rio de Janeiro: Revinter, 2001, 348p.

Fabrício MZ, Kasama ST, Martinez EZ. Qualidade de vida relacionada à voz de professores universitários. Rev CEFAC 2010;12:280-7.

http://dx.doi.org/10.1590/S1516-18462009005000062.

Costa T, Oliveira G, Behlau M. Validação do Índice de Desvantagem Vocal: 10 (IDV-10) para o português brasileiro. CoDAS 2013;25:482-5.

http://dx.doi.org/10.1590/S2317-17822013000500013

Zambon F, Moreti F, Nanquim C, Behlau M. Equivalência cultural da versão brasileira do Índice de Fadiga Vocal - VFI. CoDAS 2017; 29:e20150261. http://dx.doi.org/10.1590/2317-1782/20172015261

Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh G. An inventory for measuring depression. Arch Gen Psych 1961;4:561-71.

http://dx.doi.org/10.1001/archpsyc.1961.01710120031004

Beck AT, Brown G, Epstein N, Steer RA. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol 1988;56:893-7. http://dx.doi.org/10.1037//0022-006x.56.6.893

Hamdan AL, Farhat S, Saadeh R, El-Dahouk L, Sibai A, Yamout B. Voice-Related Quality Lify in Patients With Multiple Sclerosis. Autoimmune Dis 2012;2012:143813.

http://dx.doi.org/10.1155/2012/143813

Bauer V, Alleric Z, Jancic E, Knezevc B, Prpic D, Kacavenda A. Subjective and perceptual analysis of voice quality and relationship with neurological disfunction in multiple sclerosis patients. Clin Neurol Neurosurg 2013;115 (Suppl 1):S17-20.

http://dx.doi.org/10.1016/j.clineuro.2013.09.015

Nogueira LAC, Nóbrega FR, Lopes KN, Thuler LCS, Alvarenga MP. The effect of functional limitations and fatigue on the quality of life in people with multiple sclerosis. Arq Neuropsiquiatr 2009;67:812-7. http://dx.doi.org/10.1590/s0004-282x2009000500006

Yamout B, Fuleihan N, Hajj T, Sibai A, Sabra O, Rifai H, et al. Vocal symptoms and acoustic changes in relation to the expanded disability status scale, duration and stage of disease in patients with multiple sclerosis. Eur Arch Otorhinolaryngol 2009;266:1759-65. http://dx.doi.org/10.1007/s00405-009-1003-y

Bauer V, Aleric Z, Jancic E. Comparing Voice Self-Assessment with Auditory Perceptual Analysis in Patients with Multiple Sclerosis. Int Ach Otorhinolaryngol 2015;19:100-5. http://dx.doi.org/10.1055/s-0034-1397332

Dogan M, Midi I, Yazici MA, Kocak I, Gunal D, Sehitoglu MA. Objective and subjective evaluation of voice quality in multiple sclerosis. J Voice 2007;21:735-40.

http://dx.doi.org/10.1016/j.jvoice.2006.05.006

Anhoque CF, Domingues SCA, Carvalho T, Teixeira AL, Domingues RB. Anxiety and depressive symptoms in clinically isolated syndrome and multiple sclerosis. Arq Neuropsiquiatr 2011;69:882-6. http://dx.doi.org/10.1590/s0004-282x2011000700006

Gay MC, Bungener C, Thomas S, Vrignaud P, Thomas PW, Baker R, et al. Anxiety, emotional processinng and depression in people with multiple sclerosis. BMC Neurology 2017;17:43. http://dx.doi.org/10.1186/s12883-017-0803-8

Published

2019-12-27

Issue

Section

Artigos Originais

How to Cite

1.
Santiago R dos S, Anhoque CF. Cohort study of vocal evaluation in subjects with Multiple Sclerosis. Rev Neurocienc [Internet]. 2019 Dec. 27 [cited 2025 Dec. 13];27:1-20. Available from: https://periodicos.unifesp.br/index.php/neurociencias/article/view/9707
Received 2019-09-03
Accepted 2019-12-20
Published 2019-12-27