O Papel dos Anticorpos Antifosfolipides nos Acidentes Vasculares Cerebrais
DOI:
https://doi.org/10.34024/rnc.1994.v2.9054Palavras-chave:
Acidente Vascular Cerebral Insquemico, anticorpos antifosfolipedes, trombose, coagulaçãoResumo
Os anticorpos antifosfolipides, um grupo heterogéneo de imunoglobulinas que incluem o anticoagulante lúpico e anticardiolipina, através de sua interação com complexos proteicos fosfolipides, podem estar associados a eventos tromboticos de repetição (tanto arteriais como venosos). Podem ser observadas oclusões vasculares em todos os órgãos inclusive o cérebro. Estima-se que cerca de 20% da população com Apls positivo, possuam apresentar infartos cerebrais. Geralmente são pacientes jovens, que permaneceram com sequelas importantes. Em um estudo realizado no HCFMUSP, observou-se a presença dos ApIs em 11,8% dos pacientes jovens com AVCI. Este artigo descreve a importância da pesquisa dos Apls na investigação laboratorial quanto a etiologia dos AVCIs principalmente nos pacientes jovens.
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