Fahr's syndrome and Calda Disturbance
DOI:
https://doi.org/10.34024/rnc.1999.v7.8968Keywords:
Hypocalcemia, hypoparathyroidism, Fa hr's syndrome, basal ganglia calcificationAbstract
Basal ganglia calcifications, inappropriately called Farh's syndrome, usually ends up in Me diagnoses of hypoparathyroidism and pseudohypoparathyroidism. Neurological manifestations are frequent. Regularly, these hypocalcemic patients are seen first by the neurologist, and referred to the endocrinologist. Farh's syndrome symptoms include paresthesia, tetany, seizures, papilledema (pseudo-cerebral tumor), cataracts, extrapyramidal signs, motor and personality disturbances. A characteristic phenotype is seen in the pseudohypoparathyroidism 'la" and consists of short stature, round facies, mental retardation, obesity and brachydactily. Laboratorial findings of hypocalcemia and hyperphosphatemia in the presence of normal renal function and improper PTH values (low in the hypoparathyroidism and high in the pseudohypoparathyroidism) are the hallmarks of the diagnosis. Early treatment prevents evolution to irreversible complications and usually controls neurological manifestations.
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