Clinical and neurodevelopmental features of schizophrenia in childhood and adolescence
DOI:
https://doi.org/10.34024/rnc.2007.v15.8706Keywords:
Disorganized Schizophrenia, Motor Skills Disorders, Child, AdolescentAbstract
Objective: The present study has the main intention of describing clinical and neurodevelopmental features of schizophrenia in childhood. Method: It was a descriptive study, with 12 children and adolescents selected, of both genders, with diagnosis of schizophrenia. The information about development, signs, and symptoms of diagnosis were collected in their files. Results: Data about psychiatric phenomena of schizophrenia were identified, but it was difficult to evaluate data about neurodevelopment because of the lack of information registered in most patients’ files. Conclusion: This observation shows the stigma that surrounds schizophrenia considering it just as a psychiatric disorder.
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References
Honey GD, Pomarol-Clotet E, Corlett PR, Honey ERA, Mckenna PJ, Bullmore ET, et al. Functional dysconnectivity in Schizophrenia associated with attentional modulation of motor function. Brain 2005; 128: 2597-2611.
Alvarenga-Silva H, Teixeira-Júnior A, Costa C. Esquizofrenia de início na infância: uma revisão da apresentação clínica e da evolução. J Bras Psiquiatr 2000; 10(12): 387-393.
American Psychiatry Association. Manual Diagnóstico e Estatístico de Transtornos Mentais. 4ª edição. Porto Alegre: Artes Médicas, 2002, 880 p.
Hollis C. Developmental precursors of child-and adolescent-onset schizophrenia and affective psychoses: diagnostic specificity and continuity with symptom dimensions. Bri J Psychiatr 2003; 182: 37-44.
Hollis C. Child and adolescent (juvenile onset) schizophrenia. A case control study of premorbid developmental impairments. Bri J Psychiatr 1995; 166: 489-495.
Häffner H, Heider W, Behrens S, Gattaz WF, Hambrecht M, Löffler W, et al. Causes and consequences of the gender difference in age at onset of schizophrenia. Schizo Bull 1998; 24(2): 99-113.
Chaves AC. Diferenças entre sexos na esquizofrenia. Rev Bras Psiquiatr 2000; 22(1): 21-22.
Hogarty GE, Kornblith SJ, Greenwald D, DiBarry AL, Cooley S, Ulrich RF, et al. Three-year trials of personal therapy among schizophrenic patients living with or independent of family – description of study and effects on relapse rates. Am J Psychiatr 1997;154:1504-1513.
Hogarty GE. Does family psychoeducation have a future? Wor Psychiatr 2003; 2(1): 29-30.
Russel AT. The clinical presentation of childhood onset schizophrenia. Schizophr Bull 1994; 20: 631-646.
Chen YLR, Chen YHE, Mak FL. Soft neurological signs in schizophrenic patients and their nonpsychotic siblings. J Ner Mental Dis 2000; 188: 84-89.
Khazen CE, Chauchot F, Canceil O, Krebs MO, Baylé FJ. Les symptômes prodromiques de la schizophrénie. L’Encéphale 2003; 29(1): 469-477.
Seni, L. Genética Molecular de la Esquizofrenia. Psiquiatr Bio 1996; 4(2):73-81.
Petronis A. The origin of schizophrenia: genetic thesis, epigenetic anthithesis, and resolving synthesis. Bio Psychiatr 2004; 55(10): 965-970.
Gurling HMD, Critchley H, McQuillin A, Pimm J, Kalsi G, Lawrence J, et al. Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia. Arch Gen Psychiatr 2006; 63: 844-854.
Flyckt L, Sydow O, Bjerkenstedt L, Edman G, Rydin E, Wiesel FA. Neurological signs and psychomotor performance in patients with schizophrenia, their relatives and healthy controls. Psychiatr Res 1999; 86: 113-129.
Franck N, Georgieff N. Hypothèses neurodéveloppementales de la schizophrénie. Rev Pratic 2002; 52: 1202-1207.
Woods BT. Is schizophrenia a progressive neurodevelopmental disorder? Toward a unitary pathogenetic mechanism. Am J Psychiatr 1998; 155: 1661-1670.
Gourion D, Gourevitch R, Le Provost JB, Olié JP, Lôo H, Krebs MO. L´hypothèse neurodéveloppementale das la schizophrénie. L’Encéphale 2004; 30: 109-118.
Busatto-Filho G. A anatomia estrutural e funcional da esquizofrenia: achados de neuropatologia e neuroimagem. Rev Bras Psiquiatr 2000; 22(1): 9-11.
Fish B. Neurobiologic antecedents of schizophrenia in Children – evidence for a inherited, congenital neurointegrative defect. Arch Gen Psychiatr 1977; 34:1297-1313.
Putzhammer A, Perfahl M, Pfeiff L, Ibach B, Johann M, Zitzelsberger U, et al. Performance of diadochokinetic movements in schizophrenic patients. Schizo Res 2005; 79: 271-280.
Erlenmeyer-Kimling L. Early neurobehavioral deficits as phenotypic indicators of the schizophrenia genotype and predictors of later psychosis. Am J Med Gen (Neuropsychiatr Gen) 2001;105:23-24.
Erlenmeyer-Kimling L, Rock D, Roberts SA, Janal M, Kestenbaum C, Cornblatt B, et al. Attention, memory, and motor skills as childhood predictors of schizophrenia–related psychoses: the New York high-risk project. Am J Psychiatr 2000; 157 (9): 1416-1422.
Werner J. Análise microgenética: contribuição dos trabalhos de Vygotsky para o diagnóstico em Psiquiatria Infantil. Int J Prenatal perinatal psychol med 1999; 11(2):157-171.
