Clinical presentation of Creutzfeldt-Jakob Disease as Cerebellar Syndrome
DOI:
https://doi.org/10.34024/rnc.2009.v17.8606Keywords:
Creutzfeldt-Jakob Syndrome, Dementia, Prion DiseasesAbstract
Creutzfeldt-Jakob disease (CJD) is the most frequent prion disease in humans. A case of sporadic form of CJD is reported. A 48 year-old male presented with cerebellar syndrome compatible with CJD associated with typical electroencephalogram modification and alteration in 14-3-3 protein in cerebrospinal fluid (CSF). The clinical characteristics, laboratory findings, differential diagnosis, mechanisms of transmission and the actual therapeutic approach are discussed.
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