Effects of olive leaf on inflammation caused by metabolic disorders: a systematic review
DOI:
https://doi.org/10.34024/rnc.2024.v32.16534Keywords:
Olive Leaf, Inflammation, Systematic Review, Metabolic Disorders, Experimental StudiesAbstract
Introduction. Chronic low-grade inflammation is present in metabolic disorders such as obesity, diabetes and liver disease, and can result in lipid imbalance, oxidative stress, insulin resistance and inflammation. Olive leaves, rich in polyphenols, have beneficial effects, including antioxidant and anti-inflammatory actions. Objective. To evaluate the effects of olive leaf on inflammation caused by metabolic disorders in rats. Method. A systematic review was conducted using three electronic databases: PubMed, Scopus and Web of Science. After applying the inclusion and exclusion criteria. The evidence analysis was carried out by applying the robust tool SYRCLE’s Risk of Bias (RoB) to assess the risk of bias of the selected articles. Results. A total of 11 studies were included until August 2019 to compose this systematic review. Conclusion. Olive leaf administered to rats appears to reduce inflammatory markers in obesity, diabetes and liver disease, possibly due to the antioxidant and anti-inflammatory effects of the polyphenols present. However, current published studies are limited, requiring continuity and improvement of the intervention methodology used. More studies are needed to investigate the effects of olive leaf on inflammation in rats with metabolic disorders.
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Copyright (c) 2024 Larissa Slongo Faccioli, Anna Caroline Cristofoli Bertoletti2 Bertoletti, Isabella Rosa da Mata, Kathleen Krüger Peres, Juliano Garavaglia, Matheus Büttner Borges, Simone Morelo Dal Bosco
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Accepted 2024-09-18
Published 2024-12-17
