Efeitos dos exercícios físicos sobre a neurogênese do cérebro de ratos adolescentes
DOI:
https://doi.org/10.34024/rnc.2023.v31.14747Palavras-chave:
Exercício, Cérebro, NeurogêneseResumo
Introdução. A neurogênese do cérebro de ratos jovens pode ser afetada por diversos fatores em seu desenvolvimento, sendo a prática de exercícios físicos um fator importante na neurogênese do tecido nervoso. Objetivo. Investigar os efeitos de diferentes protocolos de exercícios físicos de média e alta intensidade na neurogênese do cérebro de ratos adolescentes. Método. O estudo experimental, onde foram utilizados três grupos de animais: um grupo controle (RC), um grupo que realizou exercício físico de média intensidade (R1) e um grupo que realizou exercício físico de alta intensidade (R2). Cada grupo com 8 animais, totalizando 24 animais. O programa de exercício físico progressivo resistido na escada vertical foi realizado durante 4 semanas, 5 dias por semana com uma duração variando entre 30 e 45 minutos. Após o término dos experimentos, os animais foram eutanasiados para retirada do encéfalo e posterior processamento, coloração pelo método de Nissl e análise histomorfométrica por contagem de neurônios no giro denteado do hipocampo e zona subventricular. Resultados. Os dados demonstraram que não houve diferença significante na área e altura do ápice do giro denteado do hipocampo entre os grupos (p=0,2474 e p=0,3337; respectivamente). Os resultados do comprimento do ápice do giro denteado do hipocampo demonstraram diferenças significantes (p=0,0172). Conclusão. A prática de exercícios físicos resistidos progressivos de média e alta intensidade não modificou a morfologia e densidade neuronal no giro denteado do hipocampo e zona subventricular de ratos jovens.
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Copyright (c) 2023 Luan Pereira Alves, Márcia Reimol de Andrade, Alessandro de Oliveira, Ismael Augusto Lima Santos, Maria Eduarda Paiva Campos, Luna Sara Campos Vaz, Laila Cristina Cristina Moreira Damázio
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Aceito: 2023-04-27
Publicado: 2023-05-18
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