Epilepsia e cardiomiopatia de Takotsubo: uma revisão de escopo

Autores

DOI:

https://doi.org/10.34024/rnc.2023.v31.14720

Palavras-chave:

Epilepsia, cardiomiopatia de Takotsubo, morte súbita

Resumo

Introdução. A incidência de morte súbita é alta em pessoas com epilepsia crônica, principalmente na presença de comorbidades cardiovasculares, desse modo, há uma convergência entre epilepsia e doenças cardiovasculares, porém a literatura carece de revisões sistemáticas acerca da interface entre epilepsia e cardiomiopatia de Takotsubo. Objetivo. Verificar a associação entre cardiomiopatia de Takotsubo e distúrbios neurológicos, especialmente epilepsia. Método. Trata-se de uma revisão de escopo, com base na lista de verificação PRISMA. Foi realizada uma busca avançada e de alta sensibilidade utilizando os descritores "epilepsy" e "Takotsubo cardiomyopathy" combinados com o operador booleano AND, nas bases de dados PubMED, Scientific Electronic Library Online, Portal Regional Biblioteca in Health e Periódicos CAPES. Resultados. Foram identificados 373 artigos e após a aplicação dos critérios de elegibilidade, foram selecionados 14 trabalhos para compor a amostra bibliográfica deste estudo. Demonstra-se a relação de pessoas com epilepsia desenvolvendo cardiomiopatia de Takotsubo, principalmente mulheres com idade avançada, com comorbidades como hipertensão arterial, diabetes mellitus e hipercolesterolemia, podendo as alterações serem evidenciadas por meio de eletrocardiograma e ecocardiograma transtorácico. Conclusão. A depressão do segmento ST na parede anterior e a inversão da onda T no eletrocardiograma podem sugerir cardiomiopatia de Takotsubo em pessoas com epilepsia, e esse monitoramento é importante devido ao potencial de convulsões levarem a problemas cardíacos. A ecocardiografia transtorácica é útil para identificar eventos adversos em pessoas com a comorbidade. O conhecimento sobre epidemiologia e os achados complementares descritos podem facilitar o raciocínio clínico para o diagnóstico e manejo da condição.

Métricas

Carregando Métricas ...

Downloads

Não há dados estatísticos.

Referências

Porto I, Della Bona R, Leo A, Proietti R, Pieroni M, Caltagirone C, et al. Stress cardiomyopathy (tako-tsubo) triggered by nervous system diseases: a systematic review of the reported cases. Int J Cardiol 2013;167:2441-8. https://doi.org/10.1016/j.ijcard.2013.01.031

Veillet-Chowdhury M, Hassan SF, Stergiopoulos K. Takotsubo cardiomyopathy: a review. Acute Card Care 2014;16:15-22. https://doi.org/10.3109/17482941.2013.869346

Mazzoli S, Fallica E, Cesnik E, Govoni V, Rispoli V, Contaldi E, et al. 34. A case of takotsubo syndrome induced by seizures. Review of letterature. Clin Neurophysiol 2017;128:e423. https://doi.org/10.1016/j.clinph.2017.09.041

Velasco IT, Neto RAB, Souza HP, Marino LO, Marchini JFM, Alencar JCG. Medicina de emergência: abordagem prática. Barueri, SP: Manole. 2022.

Dibué M, Spoor JKH, Dremmen M, Von Sab CF, Hanggi D, Steiger H-J, et al. Sudden death in epilepsy: There is room for intracranial pressure. Brain Behav 2020;10:1-11. https://doi.org/10.1002/brb3.1838

Finsterer J. Neurological Perspectives of Neurogenic Pulmonary Edema. Eur Neurol 2019;81:94-10. https://doi.org/10.1159/000500139

Costagliola G, Orsini A, Coll M, Brugada R, Parise P, Striano P, et al. The brain-heart interaction in epilepsy: implications for diagnosis, therapy, and SUDEP prevention. Ann Clin Transl Neurol 2021;8:1557-68. https://doi.org/10.1002/acn3.51382

Dupuis M, van Rijckevorsel K, Evrard F, Dubuisson N, Dupuis F, Van Robays P. Takotsubo syndrome (TKS): a possible mechanism of sudden unexplained death in epilepsy (SUDEP). Seizure 2012;21:51-4. https://doi.org/10.1016/j.seizure.2011.09.006

Verrier RL, Pang TD, Nearing BD, Schaschter SC. The Epileptic Heart: Concept and clinical evidence. Epilepsy Behav 2020;105:106946. https://doi.org/10.1016/j.yebeh.2020.106946

Ryvlin P, Rheims S, Lhatoo SD. Risks and predictive biomarkers of sudden unexpected death in epilepsy patient. Curr Opin Neurol 2019;32:205-12. https://doi.org/10.1097/WCO.0000000000000668

PRISMA. Transparent reporting of systematic reviews and meta-analyses (Internet Address). (accessed 31 August 2022). Avaiable in: http://prisma-statement.org/PRISMAStatement/PRISMAStatement

Shanaa A. Rayyan – Intelligent Systematic Review (internet address). (2021, accessed 3 September 2022). https://www.rayyan.ai/

Blanc C, Zeller M, Cottin Y, Daubail B, Vialatte AL, Giroud M, et al. Takotsubo Cardiomyopathy Following Acute Cerebral Events. Eur Neurol 2015;74:15=63-8. https://doi.org/10.1159/000440717

Belcour D, Jabot J, Grard B, Roussiaux AMD, Ferdynus C, Vandroux DMD, et al. Prevalence and Risk Factors of Stress Cardiomyopathy After Convulsive Status Epilepticus in ICU Patients. Crit Care Med 2015;43:2161-70. https://doi.org/10.1097/CCM.0000000000001191

Cammann VL, Scheitz JF, von Rennenberg R, Lancke L, Nolte CH, Szawan KA, et al. Clinical correlates and prognostic impact of neurologic disorders in Takotsubo syndrome. Sci Rep 2021;11:23555. https://doi.org/10.1038/s41598-021-01496-9

Tsuji M, Amiya E, Bujo C, Maki H, Ishida J, Hatano M, et al. Takotsubo syndrome in the same heart before and after heart transplantation. ESC Heart Fail 2020;7:4311-4. https://doi.org/10.1002/ehf2.12970

Damera N, Bangalore BS, Rao RA, Saleem K. Don’t Break My Heart: A Case Report of Takotsubo Syndrome in a Transplanted Heart. Transplant Proc 2022;54:1671-4. https://doi.org/10.1016/j.transproceed.2022.03.050

Garcia-Malvar MJ, Gonzalez-Silva Y, Epureanu-Epureanu V. Epileptic seizures complicated by Takotsubo syndrome. Rev Neurol 2014;59:407-10. https://doi.org/10.33588/rn.5909.2014348

Kyi HH, Aljariri AN, Upadhaya S, Hadidi SA. Seizure Associated Takotsubo Syndrome: A Rare Combination. Case Rep Cardiol 2017;2017:8458054. https://doi.org/10.1155/2017/8458054

Koo N, Yoon BW, Song Y, Li CK, Lee TY, Hong JY, et al. Biventricular Takotsubo Cardiomyopathy Associated with Epilepsy. J Cardiovasc Ultrasound 2015;23:262-5. https://doi.org/10.4250/jcu.2015.23.4.262

Rocha J, Gonçalves E, Vieira C, Almeida F, Pereira J, et al. Takotsubo cardiomyopathy: a rare, but serious, complication of epileptic seizures. Arq Neuropsiquiatr 2013;71:195-7. https://doi.org/10.1590/S0004-282X2013000300014

Simsek EC, Emren SV, Ozdogan O. Unusual combined cause of Takotsubo cardiomyopathy: Hyponatremia and seizure. Northern Clin Istanbul 2018;6:304-7. https://doi.org/10.14744/nci.2018.65148

Khadka B, Khanal K. View of Takotsubo Cardiomyopathy as a Complication/ Sequelae of Prolonged Refractory Seizure: A Case Report from Nepal. Arch Anesthesiol Critical Care 2021;7):297-300. https://doi.org/10.18502/aacc.v7i4.7638

Verdoia M, Viola O, Marrara F, Solda PL. A ‘shark’-masked electrocardiogram: case report of a Tako-Tsubo syndrome. Eur Heart J Case Rep 2021;5:ytab132. https://doi.org/10.1093/ehjcr/ytab132

Miller GA, Ahmed YM, Tarant NS. Recurrence of Postoperative Stress-Induced Cardiomyopathy Resulting from Status Epilepticus. Case Rep Critical Care 2017;2017:8063837. https://doi.org/10.1155/2017/8063837

Ahmed R, Sawatari H, Wafa SEI, Padmanabhan D, Deshpande S, Khanji M, et al. Impact of epilepsy or seizures on outcomes following takotsubo cardiomyopathy. Heart 2022;108:A11-12. https://doi.org/10.1136/heartjnl-2022-BCS

Finsterer J, Wahbi K. CNS disease triggering Takotsubo stress cardiomyopathy. Int J Cardiol 2014;177:322-9. https://doi.org/10.1016/j.ijcard.2014.08.101

Shmuely S, van der Lende M, Lamberts RJ, Sander JW, Thijs RD. The heart of epilepsy: Current views and future concepts. Seizure 2017;44:176-83. https://doi.org/10.1016/j.seizure.2016.10.001

Kobau R, Zahran H, Thurman DJ, 6 autores, et al. Epilepsy surveillance among adults--19 States, Behavioral Risk Factor Surveillance System, 2005. MMWR Surveill Summ 2008;57:1-20. https://pubmed.ncbi.nlm.nih.gov/18685554

Centers for Disease Control and Prevention (CDC). Comorbidity in adults with epilepsy--United States, 2010. MMWR Morb Mortal Wkly Rep 2013;62:849-53. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6243a2.htm#:~:text=This%20study%2C%20based%20on%20the,frequently%20than%20respondents%20without%20epilepsy

Keezer MR, Sisodiya SM, Sander JW. Comorbidities of epilepsy: current concepts and future perspectives. Lancet Neurol 2016;15:106-15. https://doi.org/10.1016/S1474-4422(15)00225-2

Nagai M, Förster CY, Dote K. Sex Hormone-Specific Neuroanatomy of Takotsubo Syndrome: Is the Insular Cortex a Moderator? Biomolecules 2022. https://doi.org/10.3390/biom12010110

Gaitatzis A, Carroll K, Majeed A, Sander JW. The epidemiology of the comorbidity of epilepsy in the general population. Epilepsia 2004;45:1613-22. https://doi.org/10.1111/j.0013-9580.2004.17504.x

Elliott JO, Moore JL, Lu B. Health status and behavioral risk factors among persons with epilepsy in Ohio based on the 2006 Behavioral Risk Factor Surveillance System. Epilepsy Behav 2008;12:434-44. https://doi.org/10.1016/j.yebeh.2007.12.001

Ghadri J-R, Wittstein IS, Prasad A, Sharkey S, Dote K, Akashy YJ, et al. International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management. Eur Heart J 2018;39:2047-62. https://doi.org/10.1093/eurheartj/ehy077

Lemke DM, Hussain SI, Wolfe TJ, Torbey MA, Lynch JR, Carlin A, et al. Takotsubo cardiomyopathy associated with seizures. Neurocrit Care 2008;9:112-7. https://doi.org/10.1007/s12028-008-9075-x

Desai R, Singh S, Patel U, Fong HK, Kaur KP, Varma Y, et al. Frequency of takotsubo cardiomyopathy in epilepsy-related hospitalizations among adults and its impact on in-hospital outcomes: A national standpoint. Int J Cardiol 2020;299:67-70. https://doi.org/10.1016/j.ijcard.2019.07.034

Downloads

Publicado

2023-04-19

Como Citar

Laguna, G. G. de C., Fonseca, Y. S. ., Mascarenhas, A. G. ., Ribeiro, D. B. ., Maia, M. C. ., Paulo, K. K. de S. ., … Costa, D. T. . (2023). Epilepsia e cardiomiopatia de Takotsubo: uma revisão de escopo. Revista Neurociências, 31, 1–16. https://doi.org/10.34024/rnc.2023.v31.14720

Edição

Seção

Artigos de Revisão
Recebido: 2023-01-03
Aceito: 2023-04-05
Publicado: 2023-04-19

Artigos Semelhantes

1 2 3 4 5 6 7 8 9 > >> 

Você também pode iniciar uma pesquisa avançada por similaridade para este artigo.

Artigos mais lidos pelo mesmo(s) autor(es)