Functionality and respiratory function in patients with Amyotrophic Lateral Sclerosis
DOI:
https://doi.org/10.34024/rnc.2022.v30.12901Keywords:
Amyotrophic lateral sclerosis, pulmonary function, daily activitiesAbstract
Introduction. Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that affects the upper and lower motoneurons. The clinical picture involves progressive muscle weakness and respiratory failure (RI). Objective. To relate the global functionality and respiratory changes reported by ALS patients using the Amyotrophic Lateral Sclerosis Rating Functional Scale (ALSFRS- R/BR) with the results of Peak Cough Flow (PCF) and Forced Vital Capacity (FVC). Method. This is a quantitative study with an analytical cross-sectional design carried out in a rehabilitation center in Goiás. Individuals diagnosed with ALS participated in the study. Data collection was carried out through the analysis of medical records. Respiratory function was evaluated through the PCF and FVC, and the global functionality through the ALSFRS-R/BR. A correlation was made between respiratory function and global functionality assessed using the ALSFRS-R/BR with PCF and FVC. Results. 38 individuals with ALS participated in the study. The mean age was 57.68±11.23 years. There was a significant negative correlation between FVC and RI, and a significant positive correlation between the total ALSFRS-R/BR score and PCF. Conclusion. There was a positive correlation between global functionality assessed by ALSFRS-R/BR and respiratory function by PCF. Individuals who do not use ventilatory support have lower FVC values when compared to those who used it.
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Copyright (c) 2022 Letícia Cristina Lima Carvalho, Letícia Araújo de Morais, Paulo Fernando Lôbo Corrêa
This work is licensed under a Creative Commons Attribution 4.0 International License.
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Accepted 2022-04-08
Published 2022-05-27
