COVID-19 and neurological complications: a small systematic review
DOI:
https://doi.org/10.34024/rnc.2021.v29.11769Keywords:
COVID-19, SARS-CoV-2, Neurodegeneration, Neurologic complicationsAbstract
Introduction. COVID-19 is a disease caused by beta-coronavirus known as SARS-CoV-2, which triggers several manifestations related to various organ systems. In this context, neurological complications have been described in the literature, which have associated several neurological disorders with SAR-CoV-2 infection. Objective. Thus, the aim of this study was to conduct a small systematic review, correlating COVID-19 with neurodegenerative neuropathologies. Method. The following databases were used: PUBMED, RIMA and LILACS. The selected descriptors were found in the Health Sciences Descriptors (DeCS) and Medical Subject Heading Terms (MeSH) dictionary. In addiction, the descriptors following were selected: (COVID-19 OR SARS-CoV-2) AND (NEURODEGENERATION OR NEUROLOGIC COMPLICATIONS). The titles and abstracts of all those pre-selected were read and those that did not fit the methodological style were removed. The descriptors following were excluded from the findings: systematic reviews with meta-analysis, systematic reviews with meta-synthesis and letters. Several reasons led to the exclusion of articles, such as: non-causality between SARS-CoV-2 and neurological pathologies and the pre-existence of neurodegenerative conditions in individuals. Results. The main clinical findings were: Guillan-Barré syndrome, Stroke, encephalopathies, intracranial hemorrhages, anosmia and algesia. Conclusion. In conclusion, with this review, the symptoms provided by COVID-19 can vary and that in the most severe cases, they generate neurodegenerative complications. It is worth noting that further research on the subject is needed to confirm the relationship between neurodegeneration and coronavirus infection.
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References
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Accepted 2021-03-15
Published 2021-03-25
