Neurological Changes at Covid-19: A Systematic Review
DOI:
https://doi.org/10.34024/rnc.2020.v28.10949Keywords:
COVID-19, SARS-CoV-2, Neurological ManifestationsAbstract
Introduction. The disease caused by the new SARS-CoV-2, Covid-19, can infect distinct cells from the human body. Thus, the CNS cells that might get infected along with the respiratory system. Proven researches also show neurological symptoms in patients with COVID-19. Objective. To review existing bibliographic material describing the neurological impacts associated with COVID-19. Method. The search strategy for the data used included studies obtained through five databases. Each data source used the filters: title, subject and type. The Neurological descriptor was combined using the Boolean operator AND with the descriptors: Coronavirus COVID-19 and Nervous System Diseases and their respective correspondents in Portuguese. Results. Sars-cov-2 is capable of neuroinvasion, just like other types of coronaviruses. The aggressiveness of symptoms can range from milder symptoms to predisposing of acute cerebrovascular diseases, especially in patients with comorbidities (SAH and DM). Onset period of symptoms can be on average 1-2 after the appearance of respiratory symptoms. In hypertensive patients, respiratory symptoms can be alleviated, leading to greater attention for investigation and diagnosis. Conclusion. This research offers new and important clinical information on COVID-19 and neurological changes with a high contribution to healthcare professionals in broadening the visible spectrum of the disease in addition to cardiorespiratory disorders, demonstrating the clinical evolution of the disease for associated neurological manifestations. In addition to helping them to identify possible problems in patients with COVID-19 and pre-existing neurological disorders.
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Accepted 2020-10-19
Published 2020-12-02
