Miosite por Corpos de Inclusão Familiar (MCIF)

Atualização

Autores

  • Marco Orsini Physical therapist, Associate Professor of Neurologic Rehabilitation, Escola Superior de Ensino Helena Antipoff (ESEHA), Voluntary Assistant of the Department of Neurology, Universidade Federal Fluminense – UFF, Niterói-RJ, Brazil.
  • Mariana Pimentel Mello Physical Therapist and Student of the Program of Scientific Initiation, Neurology Department, UFF, Niterói-RJ, Brazil.
  • Marcos RG de Freitas Neurologist, Head of Staff, Department of Neurology, UFF, Niterói-RJ, Brazil.
  • Osvaldo JM Nascimento Neurologist, UFF, Niterói-RJ, Brazil.

DOI:

https://doi.org/10.34024/rnc.2009.v17.8579

Palavras-chave:

Miosite, Corpos de Inclusão, Doenças Neuromusculares

Resumo

Miosite por corpos de inclusão familiar é uma doença extremamente rara, caracterizada por início tardio, seletivo e com precoce envolvimento dos músculos quadríceps, flexores dos dedos e do antebraço, e ligeiro aumento nos níveis séricos de creatina cinase (CK). Histologicamente as fibras musculares apresentam vacúolos marginados e infiltrados inflamatórios. A combinação de achados clínicos, imunopatológicos, histológicos e imunogênicos indicam que esses pacientes apresentam uma doença de características similares a miosite por corpos de inclusão esporádica.

Referências

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Publicado

2009-06-30

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1.
Orsini M, Mello MP, Freitas MR de, Nascimento OJ. Miosite por Corpos de Inclusão Familiar (MCIF): Atualização. Rev Neurocienc [Internet]. 30º de junho de 2009 [citado 24º de setembro de 2026];17(2):193-5. Disponível em: https://periodicos.unifesp.br/neurociencias/article/view/8579