O Nível Sérico de Magnésio e o Prognóstico Neurológico Após Acidente Vascular Cerebral Isquêmico Agudo

  • Flávio Ramalho Romero Médico, Postgraduated student of Neurosurgery Hospital Ipiranga, São Paulo-SP, Brazil.
  • Bento Gomes de Moraes Neto Médico, Internal Medicine residente at Hospital Ipiranga – SUS, São Paulo- SP, Brazil.
  • Gabriela Araújo Munhoz Médico, Internal Medicine residente at Hospital Ipiranga – SUS, São Paulo- SP, Brazil.
  • Eberval G. Figueiredo Médico, Head of Neurovascular Group of Neurosurgery Division of Hospital das Clínicas of Medical School of São Paulo University, São Paulo-SP, Brazil.
Palavras-chave: Níveis Séricos de Magnésio, AVE, Prognóstico Neurológico

Resumo

Introdução. O Acidente Vascular Cerebral Isquêmico á a segunda causa mais comum de morte no mundo. Cerca de um terço dos sobre­viventes são funcionalmente dependentes em 1 ano. Agentes de prote­ção cerebral permanecem o principal desafio de pesquisas. Muitos en­saios clínicos tentaram provar a eficácia da administração de magnésio nestes pacientes, mas nenhum investigou a relação entre níveis séricos de magnésio e o prognóstico. Método. Analisamos prospectivamente 83 pacientes através de estudo tipo coorte entre 2009 e 2010 e prog­nóstico em 30 e 90 dias foi avaliado. Modelo de regressão de Cox e Kaplan Meier foram usados para determinar características subjetivas associadas ao risco de recorrência. Níveis séricos de Magnésio foram dosados diariamente durante a permanência hospitalar. A indepen­dência funcional foi definida como níveis nas Escala Prognóstica de Glasgow 4 ou 5 e Escala de Rhankin modificada 0 a 2. Resultados. Magnésio < 1,8 mg/dl foi encontrado em 20 dos 83 pacientes (24%). Não houve efeito de baixos níveis séricos de magnésio nas taxas de independência funcional (28% versus 29%, P=0.84) ou mortalidade (46% versus 45%, P=0.93). Conclusão. Os níveis séricos de Mag­nésio não foram associados com pior prognóstico em nossa série de pacientes.

Métricas

Carregando métricas...

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Publicado
2012-09-30
Como Citar
Romero, F. R., Neto, B. G. de M., Munhoz, G. A., & Figueiredo, E. G. (2012). O Nível Sérico de Magnésio e o Prognóstico Neurológico Após Acidente Vascular Cerebral Isquêmico Agudo. Revista Neurociências, 20(3), 468-472. https://doi.org/10.4181/RNC.2012.20.711.5p
Seção
Revisão de Literatura