Os Agonistas Dopaminérgicos e a Qualidade de Vida na Doença de Parkinson
DOI:
https://doi.org/10.34024/rnc.2006.v14.8763Palavras-chave:
Doença de Parkinson, Qualidade de Vida, Agonistas dopaminérgicos, RevisãoResumo
A doença de Parkinson é uma doença neurodegenerativa em que os sintomas motores predominantes são resultado da morte das células da via nigro-estriatal e conseqüente depleção dopaminérgica no estriado. Os agonistas dopaminérgicos são drogas que atuam diretamente nos receptores de dopamina e sua utilização terapêutica está associada a uma menor freqüência de flutuações motoras em relação ao tratamento com levodopa. O complexo tratamento dessa doença deve ter como um dos objetivos a melhora na qualidade de vida dos pacientes. Os agonistas dopaminérgicos produzem efeito positivo sobre essa variável, possivelmente por diminuírem as complicações do tratamento e possivelmente aliviarem os sintomas depressivos.
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Publicado: 2006-06-30