Papel dos canais iônicos na Doença de Alzheimer
DOI:
https://doi.org/10.34024/rnc.2009.v17.8574Palavras-chave:
Canais Iônicos, Doença de Alzheimer, Peptídeo, TerapiaResumo
A hipótese sobre a participação dos canais iônicos na patogênese da doença de Alzheimer (DA) sugere que o peptídeo beta-amilóide (Aβ), acumulado em placas depositadas no cérebro, provoque lesão ou até morte de neurônios pela formação de canais na membrana celular. Evidências encontradas em vários estudos têm demonstrado isso. O objetivo desta revisão é analisar o papel dos canais iônicos na fisiopatologia da DA.
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Publicado: 2009-06-30
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