Vitaminas do Complexo B, Cognição e Hiper-Homocisteinemia
Uma Revisão
DOI:
https://doi.org/10.34024/rnc.2012.v20.8305Palavras-chave:
Homocisteína, Revisão Sistemática, Suplementação VitamínicaResumo
Introdução. São conhecidos vários fatores que ajudam a prever os ataques cardíacos e derrames, mas, durante os últimos anos, níveis sanguíneos elevados de homocisteína (Hcy) têm sido ligados ao aumento do risco de doença coronariana prematura e derrame. Diante de vários estudos, pode-se observar uma grande interação como seus elevados níveis de Hcy com um retardo na cognição. Objetivo. Com isso, esta revisão tem o objetivo de identificar o possível tratamento com vitaminas do complexo B, contribui na redução dos níveis plasmáticos de Hcy e na melhora da cognição. Método. Uma revisão de literatura utilizando uma pesquisa em bases de dados dos últimos dez anos, com as palavras-chaves de língua inglesa “homocysteine”, “cognitive function” e “riboflavin”. Resultados. Foram encontrados apenas vinte e quatro artigos nas bases de dados utilizadas: Pubmed, Scielo, Medline e base Cochrane. Após avaliação segundo o critério de Oxman e Guyatt e a escala de Jadad, foram tabulados somente doze artigos, pois apenas estes foram considerados adequados ou alcaçaram a pontuação mínima. Conclusão. Os achados sugerem importante beneficio na suplementação dessas vitaminas na melhora da cognição, embora nesse estudo não se pode identificar qual a vitamina do complexo B que seria essencial no controle desse processo.
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Publicado: 2012-03-31