Estimulação transcraniana por corrente contínua em fibromialgia: uma revisão sistemática

Autores

  • Alisson Alexandre da Silva Centro Universitário da Grande Dourados
  • Elaine Kakuta
  • Eduardo Henrique Loreti

DOI:

https://doi.org/10.34024/rnc.2020.v28.10884

Palavras-chave:

Fibromialgia, estimulação transcraniana por corrente contínua, dor, dor crônica, doenças reumáticas

Resumo

Introdução. A fibromialgia afeta a saúde física e mental da população e é caracterizada por alterações na atividade cerebral. A estimulação transcraniana por corrente contínua (tDCS) é uma técnica não invasiva capaz de modular a excitabilidade cortical cerebral. Objetivo. Sistematizar e discutir os efeitos da ETCC na melhora da dor em pacientes com fibromialgia quando comparado ou associado à outras técnicas, partindo dos seguintes questionamentos: A eletroestimulação transcraniana por corrente contínua é eficaz para a melhora da dor? Modifica as características clínicas da doença? Método. Foram selecionados artigos publicados entre 2015 e 2020 das bases de dados Scielo, MEDLINE, Web of Science e PEDro. Resultados. Foram selecionados 9 artigos, dos quais 6 demonstraram resultados positivos na modulação da dor com estímulo anódico em M1, 2 em CPFDL e 1 em CPFDL + C2. Conclusão. A técnica se mostrou eficaz para a modulação da dor em pacientes com fibromialgia. No entanto, são necessários mais estudos com objetivo de definir a quantidade de sessões ideal, intervalos entre as sessões e dosagem.

Downloads

Não há dados estatísticos.

Métricas

Carregando Métricas ...

Referências

Fregni F, Boggio PS, Brunoni AR. Neuromodulação terapêutica. São Paulo: Sarvier Editora de Livros Médicos LTDA, 2012.

Cummiford CM, Nascimento TD, Foerster BR, Clauw DJ, Zubieta JK, Harris RE, et al. Changes in resting state functional connectivity after repetitive transcranial direct current stimulation applied to motor córtex in fibromyalgia patients. Arth Res Therap 2016;18:40.

https://doi.org/10.1186/s13075-016-0934-0

Villafaina S, Collado-Mateo D, Domínguez-Muñoz FJ, Fuentes-García JP, Gusi N. Impact of adding a cognitive task while performing physical fitness tests in women with fibromyalgia: A cross-sectional descriptive study. Medicine 2018;97:e13791.

https://doi.org/10.1097/MD.0000000000013791

Häuser W, Fitzcharles MA. Facts and myths pertaining to fibromyalgia. Dialogues Clin Neurosci 2018;20:53-62. https://doi.org/10.31887/DCNS.2018.20.1/whauser

Muraleetharan D, Fadich A, Stephenson C, Garney W. Understanding the Impact of Fibromyalgia on Men: Findings From a Nationwide Survey. Am J Men Health 2018;12:952-60.

https://doi.org/10.1177/1557988317753242

Larsson A, Palstam A, Bjersing J, Löfgren M, Ernberg M, Kosek E, et al. Controlled, cross-sectional, multi-center study of physical capacity and associated factors in women with fibromyalgia. BMC Musculoskeletal Dis 2018;19:121. https://doi.org/10.1186/s12891-018-2047-1

Mendonça ME, Simis M, Grecco LC, Battistella LR, Baptista AF, Fregni F. Transcranial Direct Current Stimulation Combined with Aerobic Exercise to Optimize Analgesic Responses in Fibromyalgia: A Randomized Placebo-Controlled Clinical Trial. Front Hum Neurosci 2016;10:68. https://doi.org/10.3389/fnhum.2016.00068

Santos VS, Zortea M, Alves RL, Naziazeno CCS, Saldanha JS, Carvalho SCR, et al. Cognitive effects of transcranial direct current stimulation combined with working memory training in fibromyalgia: a randomized clinical trial. Sci Rep 2018;8:12477. https://doi.org/10.1038/s41598-018-30127-z

Silva AF, Zortea M, Carvalho S, Leite J, Torres ILS, Fregni F, et al. Anodal transcranial direct current stimulation over the left dorsolateral prefrontal cortex modulates attention and pain in fibromyalgia: randomized clinical trial. Sci Rep 2017;7:135. https://doi.org/10.1038/s41598-017-00185-w

Foerster BR, Nascimento TD, Deboer M, Bender MA, Rice IC, Truong DQ, et al. Excitatory and inhibitory brain metabolites as targets of motor cortex transcranial direct current stimulation therapy and predictors of its efficacy in fibromyalgia. Arth Rheumatol 2015;67:576-81. https://doi.org/10.1002/art.38945

Junior LHJ, Costa MDL, Neto LHJ, Ribeiro JPM, Freitas JSN, Teixeira MJ. Estimulação elétrica transcraniana por corrente contínua em fibromialgia: efeitos sobre a dor e a qualidade de vida, avaliados clinicamente e por cintilografia de perfusão cerebral. Rev Dor 2015;16:37-42. https://doi.org/10.5935/1806-0013.20150008

Khedr EM, Omran EAH, Ismail NM, El-Hammady DH, Goma SH, Kotb H, et al. Effects of transcranial direct current stimulation on pain, mood and serum endorphin level in the treatment of fibromyalgia: a double blinded randomized clinical trial. Brain Stimul 2017;10:893-901. https://doi.org/10.1016/j.brs.2017.06.006

Fagerlund AJ, Hansen O, Aslaksen PM. Transcranial direct current stimulation as a treatment for patients with fibromyalgia. Pain 2015;156:62-71. https://doi.org/10.1016/j.pain.0000000000000006

To WT, James E, Ost J, Hart J Jr, De Ridder D, Vanneste S. Differential effects of bifrontal and occipital nerve stimulation on pain and fatigue using transcranial direct current stimulation in fibromyalgia patients. J Neural Transm 2017;124:799-808. https://doi.org/10.1007/s00702-017-1714-y

Castillo-Saavedra L, Gebodh N, Bikson M. Clinically Effective Treatment of Fibromyalgia Pain With High-Definition Transcranial Direct Current Stimulation: Phase II Open-Label Dose Optimization. J Pain 2016;17:14-26. https://doi.org/10.1016/j.jpain.2015.09.009

Zanette AS. Sistema modulador descendente da dor na fibromialgia: mediadores séricos e efeito da melatonina. Ensaio clínico fase II, Double-dummy, controlado (Tese). Porto Alegre: Faculdade de Medicina da Universidade Federal de Rio Grande do Sul, 2014. https://lume.ufrgs.br/bitstream/handle/10183/98468/000922631.pdf?sequence=1&isAllowed=y

Porreca F, Ossipov MH, Gebhart GF. Chronic pain and medullary descending facilitation. Trends Neurosci 2002;25:319-25. https://doi.org/10.1016/s0166-2236(02)02157-4

Lamont LA, Tranquilli WJ. Physiology of Pain. Vet Clin North Am Small Anim Pract 2000;30:703-28. https://doi.org/10.1016/s0195-5616(08)70003-2

Gandiga PC, Hummel FC, Cohen LG. Transcranial DC stimulation (tDCS): A tool for doubleblind sham-controlled clinical studies in brain stimulation. Clin Neurophysiol 2006;117:845–50.

https://doi.org/10.1016/j.clinph.2005.12.003

Nitsche MA, Paulus W. Excitability changes induced in the human motor córtex by weak transcranial direct current stimulation. J Physiol 2000;527:633-9. https://doi.org/10.1111/j.1469-7793.2000.t01-1-00633.x

Villamar MF, Wivatvongvana P, Patumanond J, Bikson M, Truong DQ, Datta A, et al. Focal modulation of the primary motor cortex in fibromyalgia using 4×1-ring high-definition transcranial direct current stimulation (HD-tDCS): immediate and delayed analgesic effects of cathodal and anodal stimulation. J Pain 2013;14:371-83. https://doi.org/10.1016/j.jpain.2012.12.007

Vaseghi B, Zoghi M, Jaberzadeh S. A meta-analysis of site-specific effects of cathodal transcranial direct current stimulation on sensory perception and pain. PLoS One 2015;10:e0123873. https://doi.org/10.1371/journal.pone.0123873

Lloyd DM, Wittkopf PG, Arendsen LJ, Jones AKP. Is transcranial direct current stimulation (tDCS) effective for the treatment of pain in fibromyalgia? A systematic review and meta-analysis. J Pain 2020;S1526-5900(20)30004-3. https://doi.org/10.1016/j.jpain.2020.01.003

Deus-Yela J, Soler MD, Pelayo-Vergara R, Vidal-Samso J. Transcranial direct current stimulation for the treatment of fibromyalgia: a systematic review. Rev Neurol 2017;65:353-60. https://doi.org/10.33588/rn.6508.2017025

Pinto CB, Teixeira CB, Duarte D, Fregni F. Transcranial Direct Current Stimulation as a Therapeutic Tool for Chronic Pain. J ECT 2018;34:e36-50. https://doi.org/10.1097/YCT.0000000000000518

Zhu CE, Yu B, Zhang W, Chen WH, Qi Q, Miao Y. Effiectiveness and safety of transcranial direct current stimulation in fibromyalgia: a systematic review and meta-analysis. J Rehabil Med 2017;49:2-9. https://doi.org/10.2340/16501977-2179

Charvet LE, Kasschau M, Datta A, Knotkova H, Stevens MC, Alonzo A, et al. Remotely-supervised transcranial direct current stimulation (tDCS) for clinical trials: guidelines for technology and protocols. Front Syst Neurosci 2015;9:26. https://doi.org/10.3389/fnsys.2015.00026

Downloads

Publicado

2020-11-03

Como Citar

Silva, A. A. da, Kakuta, E., & Henrique Loreti, E. (2020). Estimulação transcraniana por corrente contínua em fibromialgia: uma revisão sistemática. Revista Neurociências, 28, 1–18. https://doi.org/10.34024/rnc.2020.v28.10884

Edição

Seção

Revisão Sistemática
Recebido: 2020-07-06
Aceito: 2020-10-21
Publicado: 2020-11-03

Artigos mais lidos pelo mesmo(s) autor(es)